Compugen's Therapeutics Programs consist of therapeutic candidates that have been initially predicted in silico utilizing our proprietary discovery platform(s), and then successfully demonstrated functional activity in vitro and in vivo.
The therapeutic protein and peptide product candidates listed to the left are among those discovered or further validated largely as a result of validation activities with respect to our various discovery platforms. However, during 2010 we shifted the focus of our discovery efforts from this “technology driven”, platform by platform approach to a “market-need driven” basis, pursuant to which we, either on our own or with a partner company, will identify an unmet therapeutic need where we believe our predictive capabilities would be relevant, or could be modified to be relevant. In this market need driven approach, our goal is to harness all of our relevant capabilities towards the specific unmet need, rather than relying on a single discovery platform as was the case previously. Our discovery efforts are focused primarily in the fields of immunology and oncology.
In 2010 we initiated our Pipeline Program pursuant to which we intend to both (i) substantially increase the number of predicted and selected product candidates being evaluated by us, and (ii) take selected product candidates further beyond their proof of concept into preclinical activities.